Even 2C-B, which is by far the most popular, has never been examined in a clinical setting. They’re members of the greater phenethylamine class of psychedelics and are characterized by the presence of 2 carbon atoms located between a benzene ring and an amino group (hence the name “2C,” which implies “2 carbons”). At PsychedelicsDaily.com, I believe in the responsible and intentional use of psychedelics, and I am committed to harm reduction and education. If you have any questions or comments related to psychedelics, microdosing, consciousness exploration, or harm reduction, please don’t hesitate to reach out to us.
- This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
- You’ll begin to experience effects about minutes after taking 2C-B-FLY, and the effects usually last between six and twelve hours.
- Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history.
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Do not, however, start with a strong dose if you don’t have a trip sitter nearby.High doses can easily cause you to reach a breakthrough where you lose sense of the physical world. There are people who can take relatively high doses and feel nothing. 2C-B-FLY belongs to a group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” tetrahydrofuran rings fused on the opposite sides of the central benzene ring. The incorporation of the two methoxy groups into the 5 member rings fixes them into the optimum position for binding to the receptors they interact with resulting in an increase in potency compared to the compound’s non-rigid 2c-b-fly counterpart 2C-B.
What is 2C-B-FLY?
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination. Much like 2C compounds, the most prominent 3C substances were discovered by Alexander Shulgin.
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Shulgin referred to it as “pharmacological tofu” because he believed it could potentiate the psychedelic effects of other compounds but lacked any significant “psychedelic flavor” of its own. In theory, dihydrodifuran analogues of any of the 2Cx / DOx family of drugs could be made, and would be expected to show similar activity to the parent compound. So in the same way that 2C-B-FLY is the dihydrodifuran analogue of 2C-B, the 8-iodo equivalent 2C-I-FLY would be the dihydrodifuran analogue of 2C-I, and the 8-methyl equivalent 2C-M-FLY would be the dihydrodifuran analogue of 2C-D. In terms of dosage, both compounds are comparable — active in the 5 – 20 mg range, with a threshold somewhere around 5 mg.
The key features of 2C-B-FLY include:
Learning about the 2Cs is one of the best ways to understand psychedelic chemistry. The legendary chemist, Alexander Shulgin, created the group by systematically modifying the base molecule for mescaline by adding slightly different functional groups to one side of the molecule and then testing their effects. The most popular members of the group are 2C-B and 2C-I — but there are dozens of other compounds that share similar effects. Most people have heard of mescaline, LSD, and MDMA — but only serious psychonauts are familiar with the 2C substances.
After effects
2C-B-FLY is a psychedelic substance of the of the phenethylamine and benzodihydrodifuran classes. Even though 2C-B FLY is structurally similar to 2C-B, the effects of those drugs are not the same. The full name of the chemical is 2-(8-bromo-2,3,6,7-tetrahydrofuro2,3-f 1benzofuran-4-yl)ethanamine.
In it, they list their favorite compounds, which were aptly named the “magical half-dozen.” Most of these compounds are 2Cs, with the exception of mescaline (the starting point for all 2Cs, and DOM, which is an amphetamine). 2C substances are modeled after mescaline and are thought to work through similar mechanisms. The safety of this compound, as with many other 2C compounds, is unknown. It’s hard to make and doesn’t produce nearly as potent psychedelia as most of the other 2C substances. Some people take sub-perceptual microdoses of 2C-I as a nootropic (less than 8 mg).
LSD, magic mushrooms, and other psychedelics don’t often share this same sentiment. Psychoactive doses make it very difficult to perform normal activities, let alone interact with other people. The threshold is reported around 5 mg, and the standard psychoactive dose is between 10 and 25 mg. 2C-B-FLY is unscheduled and uncontrolled in the United States, which means it is currently legal to buy. It’s also legal in much of Europe, but 2C-B-FLY is a controlled substance (Schedule III) in Canada.
It is a very practical molecule for exploring the arts, I found myself writing poetry and lyrics for hours inspired by a single 10mg dose. Spending the day in a park or a forest is easy to manage with the small doses. You can really lose yourself in the appreciation of life like a child smiling at the reflection of sunlight on a puddle. Although the majority of 2C-X were discovered and synthesized by Alexander Shulgin, 2C-B-FLY was discovered by Aaron P. Monte in 1996. The name “FLY” (2C-B-Fly) was inspired by the two dihydrofuran rings that run opposite the sides of the benzene ring. It is not about your age, it is about how mature you are.Teenagers (and younger) generally aren’t responsible enough to take psychedelics but it isn’t always the case.If you are under the age of 21, your brain is evolving at a rapid rate on its own.
Dosage of 2C-B-FLY
The trade-off is that 2C-G has much milder visual and tactile effects. The incorporation of the two methoxy groups into the 5 member rings fixes them into the optimum position for binding to the receptors they interact with resulting in an increase in potency compared to the compound’s non-rigid counterpart 2C-B. 2C-B, or 2,5-dimethoxy-4-bromophenethylamine, is a substituted phenethylamine. Substituted phenethylamines are a chemical class of organic compounds that are based upon the phenethylamine structure, a phenyl ring bound to an amino (NH2) group through an ethyl chain.
There’s evidence to suggest some 2C compounds could be used in psychedelic-assisted psychotherapy, and some claim microdosing 2C substances are useful as a source of nootropic compounds. Both 2C substances and amphetamines are members of the larger phenethylamine group but feature differences that alter the way these molecules are able to bind to receptors in the brain. Amphetamines tend to have a higher affinity for the dopamine receptors, while 2C prefers the serotonin receptors. Dr. Alexander Shulgin is the genius behind most of the 2C family of compounds, along with many other phenethylamine and tryptamine psychedelics. He would create and then test each of these substances with his wife, Anne Shulgin, and a group of friends to characterize their effects. 2C-D (AKA 2C-M or LE-25) is known for its mild nature and short duration of effects.
The effects of 2C-B-FLY have been described as being quite similar to those of 2C-B. It is slightly psychedelic, much less so than mushrooms or LSD for example, and is much less empathogenically oriented than MDMA. Keep your powder or pills in a cold dark place, preferably with no air.If you don’t do this, 2C-B-Fly will lose potency within a few weeks or months.When you store the substance well, it will last for years or even decades. Vaporizing the drug instead of eating it doesn’t seem to have any benefits.
He was first overwhelmed with lots of color and then found himself astral traveling to past lives far away. His return to reality was not easy at all and his experience was very scary. This is exactly what the late Ann Shulgin recommended in the monumental TIHKAL and PIHKAL , written with her husband, Alexander Shulgin – the godfather of the vast majority of psychedelics discovered in the 80s and 90s. With 10 mg, we are dealing with an experience without too many visuals, with a lot of colors, offering a certain body heat and being able to be managed by the majority of people. A novice user will perhaps prefer 5 or 7 mg to really take the time to get used to this substance. 2C-B-Fly is a molecule allowing psychedelic exploration while being relatively soft and easy to control.
Otherwise I always mixed the cannabis with 2C-B-FLY I was just waiting for the first 3-4 hours of the high and the beginning of the plateau to pass, that I felt I had some stability with going further. With only 10 mg of 2C-B-FLY, one balloon of N20 caused me to completely take off, for 5 minutes I was in a state of intense bodyload, all the effects of 2C-B-FLY were tenfold. The effects of 2C-B-FLY can be felt as early as 5mg, but the classic dose is between 10 and 20 mg. It is important to practice risk reduction and start with the lowest dosages. The visuals are generally very soft at the classic doses ( 10 to 20 mg ), we keep a surprisingly clear mindset and there is a whole erotic and empathic side relatively similar to MDMA and 2C-B.
Side Effects of 2C-B-FLY
2C compounds range from being inactive to powerfully empathogenic and psychedelic. Some of these creations proved to be formidable psychedelics and empathogens; others were completely inactive. Psychedelics are substances (natural or laboratory made) which cause profound changes in a one’s perceptions of reality. While under the influence of hallucinogens, users might hallcuniate visually and auditorily. As with other serotonergic psychedelic, 2C-B is considered to be non-addictive with a low potential for abuse. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. Numerous people have died from taking NBOMe substances over the years — often while using doses believed to be safe. Everyone reacts differently to these compounds, and there are cases of people dying after taking just one tab. All 2C compounds contain 2 methoxy groups at the 2 and 5 positions of a central benzene ring. This leaves two additional regions for other functional groups to be attached. Shulgin would attach all kinds of different molecules to the R3 and R4 positions.
Psychedelic Research Chemicals or RC Chems are new synthetic substances which are structurally similar to the original drug, while being functional analogs. Data on their effects limited due as they’re fairly new and do not have a lot of human consumption history. 2C-B does not produce cross-tolerance with other serotonergic psychedelics, although most users report other psychedelics affecting 2C-B tolerance. For example 2C-B followed by LSD will not result in any loss of effects whereas LSD followed by 2C-B will.
Let the drug completely dissolve into the water.Use a 1 ml syringe, put the liquid into it and plug the substance into your a#s.You need to put the syringe deep enough but not too deep either. What will help you achieve this is putting a rubber band around the 0.6 ml. That way, you will know when to stop.After you pour the liquid into your system, wait for 1-2 minutes, then pour the syringe out and go lay on your bed or the ground. However, it may fall under the scope of the Federal Analog Act if it is intended for human consumption given its similarity to 2C-B. Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects.
